Goose IRF7 is involved in antivirus innate immunity by mediating IFN activation

Z Lin, J Wang, S Zhao, Y Li, Y Zhang, Y Wang… - … Immunology, 2022 - Elsevier
… This indicates that the immune systems of chickens, ducks, … effect of GoIRF7 on the expression
of innate immune genes, we … are pivotal for inducing IFN-β promoter activity and that the …

[HTML][HTML] Systematic identification of chicken type I, II and III interferon-stimulated genes

M Dai, T Xie, M Liao, X Zhang, M Feng - Veterinary research, 2020 - Springer
immunology has been lagging behind, especially in the field … anti-VSV activity analysis,
the bioactivity of the purified ChIFN-… Indeed, in our study, we found that some classic antivirus

[HTML][HTML] Molecular cloning and transcriptional regulation of Indian peafowl (Pavo cristatus) IFN-α gene

Y Wang, H Zhao, J Liu, Y Shao, M Xing - Cell Stress and Chaperones, 2019 - Elsevier
IFN-αs have been elaborated as part of the innate immune … an N-terminal detection and
purification epitope (His·Tag). After being … function, we detected its antivirus activity and made a …

Characterization of chicken IFI35 and its antiviral activity against Newcastle disease virus

YQ Jia, XW Wang, X Chen, XX Qiu… - Journal of Veterinary …, 2022 - jstage.jst.go.jp
… The PCR products were purified and cloned into the pMD19-T … Analysis chIFI35 expression
in immune-associated tissues … However, we observed that IFNexpression induced by IFI35 …

[HTML][HTML] Chicken DDX3X Activates IFN-β via the chSTING-chIRF7-IFN-β Signaling Axis

Q Niu, Y Cheng, H Wang, Y Yan, J Sun - Frontiers in immunology, 2019 - frontiersin.org
… Knockdown of chDDX3X expression resulted in reduced activity from the IFN-β … the
expression of antivirus molecules and proinflammatory cytokines as well as the expression of IFN-β.…

Effects of infectious bursal disease virus infection on interferon and antiviral gene expression in layer chicken bursa

Y Yu, Z Xu, Y Liu, H Zhang, C Ou, Y Zhang, T Liu… - Microbial …, 2020 - Elsevier
IFN-induced antiviral activity in cells forms an important early line of … IFN-α, IFN-β, IFN-γ, and
IFN-λ are essential for immune … III IFN receptors to induce the expression of hundreds of IFN-…

[HTML][HTML] Chicken Interferon-Alpha and-Lambda Exhibit Antiviral Effects against Fowl Adenovirus Serotype 4 in Leghorn Male Hepatocellular Cells

…, L Chen, F He, L Li, L Yang, T Ren, B Xiang - International Journal of …, 2024 - mdpi.com
… , IFN-α and IFN-β display distinct levels of antiviral activity, … approach for addressing the
immune prevention and control … in inclusion body expression and were purified using nickel …

Expression of duck interferon-α in silkworm baculovirus expression vector system and detection of its antiviral activity.

P Wang, XX Wang, ZZ Wei, XJ Liu, ZF Zhang… - Acta Sericologica …, 2019 - cabdirect.org
activity like broad-spectrum antivirus and antitumor, duck … chicken cells to verify the inhibition
effect of these expressed … -α was purified, its expression level increased and antiviral activity

[HTML][HTML] Chicken interferon regulatory factor 7 (IRF7) can control ALV-J virus infection by triggering type I interferon production through affecting genes related with …

Y Wang, F Yang, H Yin, Q He, Y Lu, Q Zhu… - … Immunology, 2021 - Elsevier
… in liquid nitrogen for total RNA extraction. Meanwhile, we also … To better understand the role
of the IRF7 in innate antivirus … IRF7 led to decreased expression of IFN-α and IFN-β. Based …

[HTML][HTML] Cross-species genome-wide analysis reveals molecular and functional diversity of the unconventional interferon-ω subtype

LE Shields, J Jennings, Q Liu, J Lee, W Ma… - … in Immunology, 2019 - frontiersin.org
activity assays, we synthesized several porcine IFN peptides … IFN peptides were collected
and partially purified using two … to the surges of IFN genes in amphibians, chickens, bats, …